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<p>그림 뷰어 그림 9. 서로 다른 박테리아의 CueR 단백질에서 부위 특이적 동역학 비교. (A) AlphaFold3로 예측한 P. aeruginosa CueR 구조(검은색)를 E. coli CueR 의 X선 결정 구조 (회색) 위에 겹쳐 놓고 G57R1 부위를 녹색으로 표시함. (B) 상온에서 측정한 돌연변이체의 아포 상태 CW-ESR 스펙트럼 ( E. coli , 녹색, 위쪽 ) ( P. aeruginosa , 검은색, 아래쪽 ). (C) G57R1 E. coli CueR(녹색) 및 (D) G57R1 P. aeruginosa CueR(회색)의 네 가지 다른 기능 상태. 검은색 점선은 EasySpin을 이용한 시뮬레이션 결과이다. 그림은 ( )에서 발췌함.112). 전반적으로, 이러한 비교 측정 결과는 대장균 과 녹농균 CueR에서 뚜렷하게 구분되는 Cu(I) 반응 메커니즘을 보여줍니다. 대장균 CueR은 낮은 농도의 금속 이온에서도 DNA 결합 도메인에서 즉각적인 활성 증가를 나타내며, 이는 빠른 알로스테릭 활성화 메커니즘을 반영합니다. 반면, 녹농균 CueR은 DNA 결합과 더욱 밀접하게 연관된 활성을 보이며, DNA가 없는 환경에서는 활성화를 위해 더 높은 Cu(I) 농도가 필요합니다. <a class="seoquake-nofollow" href="https://gajimall.net/" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span style="color:rgb(255,255,255);font-family:LexiSaebomR;line-height:2;letter-spacing:1px;text-decoration:none;">토토솔루션</span></a> <a class="seoquake-nofollow" href="https://xn--910br1nf9g2g92y.com/" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span style="color:rgb(255,255,255);font-family:LexiSaebomR;line-height:2;letter-spacing:1px;text-decoration:none;">리얼돌</span></a> <a 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